Retinoic acid-d3

MedChem Express

Retinoic acid-d3 [154461-49-1]

5

Research Use Only

C20H25D3O2

303.45

Retinoic acid-d3 is the deuterium labeled Retinoic acid (HY-14649). Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARalpha/beta/gamma. Retinoic acid bind to PPARbeta/delta with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2][3].

CC(/C=C/C=C(/C=C/C1=C(CCCC(C)1C)C([2H])([2H])[2H])C)=C\C(O)=O

12131703