RETRA (hydrobromide) [1035875-01-4]
HY-113843
CAS Number1035875-01-4
Product group Chemicals
Molecular Weight350.25
Overview
- SupplierMedChem Express
- Product NameRETRA (hydrobromide) [1035875-01-4]
- Delivery Days Customer9
- CAS Number1035875-01-4
- CertificationResearch Use Only
- Molecular FormulaC11H12BrNO3S2
- Molecular Weight350.25
- Scientific DescriptionRETRA (hydrobromide) is a mutant p53-dependent activator of p73 that can inhibit cancer cells carrying mutant p53. RETRA (hydrobromide) increases the expression level of p73, induces transcriptional activation of several common to transcriptional targets p53 and p73, which leads to mutant p53- and p73-dependent inhibition of tumor growth, reduction of colony formation and induction of effector caspases[1].
- SMILESO=C(CSC1=NCCS1)C2=CC=C(C(O)=C2)O.Br
- UNSPSC12352200