Reveromycin B

MedChem Express

Reveromycin B [144860-68-4]

5

144860-68-4

Research Use Only

C36H52O11

660.79

Reveromycin B is a spiroketal bacterial metabolite originally isolated from Streptomyces. It inhibits EGF-induced mitogenic activity in Balb/MK cells ( IC 50 =6 microg/mL) and exhibits pH-dependent antifungal activity against C. albicans (MICs=15.6 and >500 microg/mL at pH 3.0 and 7.4, respectively). Unlike reveromycin A and reveromycin C, reveromycin B does not inhibit proliferation of KB and K562 cells.

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