Reveromycin C
HY-125322
Overview
- SupplierMedChem Express
- Product NameReveromycin C [144860-69-5]
- Delivery Days Customer5
- CAS Number144860-69-5
- CertificationResearch Use Only
- Molecular FormulaC37H54O11
- Molecular Weight674.82
- Scientific DescriptionReveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs=2.0 and >500 microg/mL at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50=1.58 microg/mL) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50=2.0 microg/mL for both).
- SMILESO=C(O[C@@]1(CCC(C)C)[C@H](/C=C/C(C)=C/C(O)=O)O[C@]2(O[C@H](C/C=C(C)/C=C/[C@H](O)[C@@H](C)/C=C/C(O)=O)[C@@H](C)CC2)CC1)CCC(O)=O
- UNSPSC12352200