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Reveromycin C

HY-125322
MedChem Express
CAS Number144860-69-5
Product group Chemicals
Molecular Weight674.82
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Reveromycin C [144860-69-5]
  • Delivery Days Customer
    5
  • CAS Number
    144860-69-5
  • Certification
    Research Use Only
  • Molecular Formula
    C37H54O11
  • Molecular Weight
    674.82
  • Scientific Description
    Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs=2.0 and >500 microg/mL at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50=1.58 microg/mL) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50=2.0 microg/mL for both).
  • SMILES
    O=C(O[C@@]1(CCC(C)C)[C@H](/C=C/C(C)=C/C(O)=O)O[C@]2(O[C@H](C/C=C(C)/C=C/[C@H](O)[C@@H](C)/C=C/C(O)=O)[C@@H](C)CC2)CC1)CCC(O)=O
  • UNSPSC
    12352200

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