Reverse T3 ELISA Kit

Arigo Biolaboratories

Reverse T3 ELISA Kit

23

ELISA

Intra-Assay CV: less than 5.0%Inter-Assay CV: less than 8.5%

14 pg/ml

~2.5 hours

Research Use Only

HRP

Reverse T3 (rT3) is a metabolically inactive form of thyroid hormone, which is generated from T4 via the type 3 5-deiodinase enzyme. In addition to producing rT3, the type 3 5-deiodinase enzyme is also responsible for decomposing rT3 into inactive diiodothyronine. In nonthyroidal illness states, rT3 levels are elevated because of (1) increased production of rT3 from T4 and (2) reduced clearance of rT3 to diiodothyronine. In hypothyroidism, rT3 levels are typically low due to reduced production of the precursor (i.e., T4), although in mild hypothyroidism rT3 levels may sometimes be normal or high. In contrast, rT3 levels typically remain normal in kidney dysfunction.

2°C to 8°C

41116100