Bio-Connect
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA012032(RFFL Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA012032(RFFL Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA012032(RFFL Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200)

RFFL Antibody

CSB-PA012032
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetRFFL
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Cusabio
  • Product Name
    RFFL Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID117584
  • Target name
    RFFL
  • Target description
    ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  • Target synonyms
    CARP2; CARP-2; caspase 8 and 10 associated RING protein-2; caspase regulator CARP2; caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin-protein ligase rififylin; FRING; FYVE-RING finger protein SAKURA; RIFIFYLIN; ring finger and FYVE-like domain containing 1; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING-type E3 ubiquitin transferase rififylin; RNF189; RNF34L
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8WZ73
  • Protein Name
    E3 ubiquitin-protein ligase rififylin
  • Scientific Description
    E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Mediates Lys-48-linked polyubiquitination of PRR5L and its subsequent proteasomal degradation thereby indirectly regulating cell migration through the mTORC2 complex. Also ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate apoptosis downstream of death domain receptors. Also negatively regulates the tumor necrosis factor-mediated signaling pathway through targeting of RIPK1 to ubiquitin-mediated proteasomal degradation.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

Related products

Product group Antibodies
Assay Genie
TargetRFFL
  • SizePrice
Immunofluorescent staining of human cell line A-431 shows localization to vesicles.
Product group Antibodies
Atlas Antibodies
ApplicationsWestern Blot, ImmunoCytoChemistry
ReactivityHuman
TargetRFFL
  • SizePrice
Product group Antibodies
GeneTex
ApplicationsWestern Blot
TargetRFFL
  • SizePrice
Mouse Liver lysates probed with RING finger protein 189 Polyclonal Antibody, Unconjugated (bs-6872R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.
Product group Antibodies
Bioss Antibodies
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetRFFL
  • SizePrice
Product group Antibodies
LifeSpan BioSciences
RFFL AntibodyLS-C748645
ApplicationsImmunoFluorescence
TargetRFFL
  • SizePrice