RG-12525 [120128-20-3]
HY-101676
CAS Number120128-20-3
Product group Chemicals
Estimated Purity98.31
Molecular Weight423.47
Overview
- SupplierMedChem Express
- Product NameRG-12525 [120128-20-3]
- Delivery Days Customer10
- CAS Number120128-20-3
- CertificationResearch Use Only
- Estimated Purity98.31
- Molecular FormulaC25H21N5O2
- Molecular Weight423.47
- Scientific DescriptionRG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 microM.
- SMILESC1(COC2=CC=C(OCC3=CC=CC=C3CC4=NN=NN4)C=C2)=NC5=CC=CC=C5C=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![RG-12525 [120128-20-3]](https://www.targetmol.com/group3/M00/03/1B/CgoaEGY7RyWETFEbAAAAAB-2KMk128.png)