RG108

MedChem Express

RG108 [48208-26-0]

10

48208-26-0

Research Use Only

99.93

C19H14N2O4

334.33

RG108 (N-Phthalyl-L-tryptophan) is a non-nucleoside DNA methyltransferases (DNMTs) inhibitor ( IC 50 =115 nM) that blocks the DNMTs active site. RG108 (N-Phthalyl-L-tryptophan) causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences [1] [2] [3] .

O=C(N1[C@H](C(O)=O)CC2=CNC3=C2C=CC=C3)C4=CC=CC=C4C1=O

-20°C,2°C to 8°C

12352200