RG7112

MedChem Express

RG7112 [939981-39-2]

10

939981-39-2

Research Use Only

99.91

C38H48Cl2N4O4S

727.78

RG7112 is a potent, selective, first clinical, orally active and blood-brain barrier crossed MDM2-p53 inhibitor, with an IC 50 of 18 nM and a K D of 11 nM for binding to MDM2 [1] .

C[C@@]1([C@](C)(N(C(C2=CC=C(C=C2OCC)C(C)(C)C)=N1)C(N3CCN(CC3)CCCS(=O)(C)=O)=O)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

-20°C,2°C to 8°C

12352200