ProductsBack/Rhizopodin [150346-23-9]

Rhizopodin [150346-23-9]

Name: Rhizopodin [150346-23-9]
SKU: HY-120883_M09
Availability: BackOrder

HY-120883

CAS Number150346-23-9

Product group Chemicals

Molecular Weight1469.83

Overview

Supplier
MedChem Express
Product Name
Rhizopodin [150346-23-9]
Delivery Days Customer
5
CAS Number
150346-23-9
Certification
Research Use Only
Molecular Formula
C78H124N4O22
Molecular Weight
1469.83
Scientific Description
Rhizopodin is a new cytostatic compound isolated from the culture fluid of the slime mold Myxococcus stipitatus. Rhizopodin inhibits the growth of various animal cell cultures without killing the cells, with an ID50 value of 12 to 30 ng/ml, depending on the cell line. In particular, fibroblast-like cells show typical morphological changes, with cells becoming larger and forming long branched reticular extensions within hours, and these morphological changes are irreversible. Rhizopodin inhibits bleb formation in K-562 cells, possibly through interaction with protein phosphorylation.
SMILES
CO[C@]1([H])C2=COC(C[C@@H](C(C)([C@@H](OC(C[C@H](C[C@H](/C=C/C=C/C[C@@](OC)([H])C3=COC(C[C@H](O)C(C)(C)[C@H](C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)OC(C[C@@H](O)C[C@@H](OC)/C=C/C=C/C1)=O)=N3)OC)O)=O)C[C@H](OC)[C@@H](C)CCC([C@H](C)[C@H](OC)C/C=C/N(C)C=O)=O)C)O)=N2
UNSPSC
12352200