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RI-1

HY-15317
MedChem Express
CAS Number415713-60-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight361.61
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RI-1 [415713-60-9]
  • Delivery Days Customer
    10
  • CAS Number
    415713-60-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C14H11Cl3N2O3
  • Molecular Weight
    361.61
  • Scientific Description
    RI-1 is a RAD51 inhibitor, with IC50s ranging from 5 to 30 microM. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319. RI-1 inactivates RAD51 by directly binding to a protein surface that serves as an interface between protein subunits in RAD51 filaments. RI-1 can disrupt homologous recombination in human cells[1].
  • SMILES
    O=C(C(N1CCOCC1)=C2Cl)N(C3=CC=C(Cl)C(Cl)=C3)C2=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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