IHC-P analysis of kidney tissue using GTX83714 RIC8A antibody [3G3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
![WB analysis of human tissues (Lane 1-Testis ; Lane 2-Omentum ; Lane 3-Uterus ; Lane 4-Breast ; Lane 5-Brain ; Lane 6-Liver ; Lane 7-Ovary ; Lane 8-Thyroid gland ; Lane 9-colon ; Lane 10-spleen) using GTX83714 RIC8A antibody [3G3]. Loading : 10 ug per lane Dilution : 1:200](https://www.genetex.com/upload/website/prouct_img/normal/GTX83714/GTX83714_3734_WB_w_23061420_379.webp "WB analysis of human tissues (Lane 1-Testis ; Lane 2-Omentum ; Lane 3-Uterus ; Lane 4-Breast ; Lane 5-Brain ; Lane 6-Liver ; Lane 7-Ovary ; Lane 8-Thyroid gland ; Lane 9-colon ; Lane 10-spleen) using GTX83714 RIC8A antibody [3G3]. Loading : 10 ug per lane Dilution : 1:200")
![WB analysis of HEK293T cells transfected with RIC8A plasmid (Right) or empty vector (Left) for 48 hrs using GTX83714 RIC8A antibody [3G3]. Loading : 5 ug per lane](https://www.genetex.com/upload/website/prouct_img/normal/GTX83714/GTX83714_3842_WB_w_23061420_840.webp "WB analysis of HEK293T cells transfected with RIC8A plasmid (Right) or empty vector (Left) for 48 hrs using GTX83714 RIC8A antibody [3G3]. Loading : 5 ug per lane")
![ICC/IF analysis of COS7 cells transiently transfected with RIC8A plasmid using GTX83714 RIC8A antibody [3G3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83714/GTX83714_786_ICCIF_w_23061420_837.webp "ICC/IF analysis of COS7 cells transiently transfected with RIC8A plasmid using GTX83714 RIC8A antibody [3G3].")
![ICC/IF analysis of HepG2 cells using GTX83714 RIC8A antibody [3G3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83714/GTX83714_787_ICCIF_w_23061420_381.webp "ICC/IF analysis of HepG2 cells using GTX83714 RIC8A antibody [3G3].")
IHC-P analysis of kidney tissue using GTX83714 RIC8A antibody [3G3]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min. Dilution : 1:50
RIC8A antibody [3G3] - Overexpression Validated
GTX83714
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetRIC8A
Overview
- SupplierGeneTex
- Product NameRIC8A antibody [3G3] - Overexpression Validated
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3G3
- Concentration0.83 mg/ml
- ConjugateUnconjugated
- Gene ID60626
- Target nameRIC8A
- Target descriptionRIC8 guanine nucleotide exchange factor A
- Target synonymsresistance to inhibitors of cholinesterase 8 homolog A; RIC8; synembryn-A
- HostMouse
- IsotypeIgG1
- Scientific DescriptionGuanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203