Ridaforolimus [572924-54-0]

MedChem Express

Ridaforolimus [572924-54-0]

10

572924-54-0

CHEMICAL,general_chemicals_reagents

Research Use Only

99.75

C53H84NO14P

990.21

Ridaforolimus (MK-8669) is a potent and selective mTOR inhibitor; inhibits ribosomal protein S6 phosphorylation with an IC50 of 0.2 nM in HT-1080 cells[1].

O=C(C([C@](O[C@]1([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H]2C)OC)([C@@H](CC1)C)O)=O)N(CCCC3)[C@]3([H])C(O[C@](CC([C@@H](/C=C([C@H]([C@H](C([C@H](C)C2)=O)OC)O)\C)C)=O)([H])[C@H](C)C[C@H](CC[C@H]4OP(C)(C)=O)C[C@H]4OC)=O

-20°C, 3 years; 4°C, 2 years (Powder)

12352005