Rifamycin AF-O13 [35225-13-9] [35225-13-9]

Bioss

Rifamycin AF-O13 [35225-13-9] [35225-13-9]

16

35225-13-9

Research Use Only

Unconjugated

>95%

C46H64N2O13

853

Ansamycin antibiotic. Potent inhibitor of nucleic acid polymerizing enzymes and of some hormone receptors. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Inhibitor of RNA-dependent DNA polymerase of MSV. Effective against mycobacteria and therefore might be used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.

OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@H]2C)O)=O)C(/C=N/OCCCCCCCC)=C(O)C3=C4C(O[C@@](O/C=C/[C@H](OC)[C@H]([C@H]2OC(C)=O)C)(C)C4=O)=C(C)C(O)=C31

-20°C

12161600