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Rilmenidine (hemifumarate)

HY-100490A
MedChem Express
CAS Number207572-68-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.82
Molecular Weight238.28
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rilmenidine (hemifumarate) [207572-68-7]
  • Delivery Days Customer
    10
  • CAS Number
    207572-68-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.82
  • Molecular Formula
    C10H16N2O.1/2C4H4O4
  • Molecular Weight
    238.28
  • Scientific Description
    Rilmenidine hemifumarate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine hemifumarate is an alpha 2-adrenoceptor agonist. Rilmenidine hemifumarate induces autophagy. Rilmenidine hemifumarate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na + /H + antiport. Rilmenidine hemifumarate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells [1] [2] [3] .
  • SMILES
    O=C(O)/C=C/C(O)=O.C1(NC(C2CC2)C3CC3)=NCCO1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200