Rilmenidine (hemifumarate)

MedChem Express

Rilmenidine (hemifumarate) [207572-68-7]

10

207572-68-7

99.82

C10H16N2O.1/2C4H4O4

238.28

Rilmenidine hemifumarate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine hemifumarate is an alpha 2-adrenoceptor agonist. Rilmenidine hemifumarate induces autophagy. Rilmenidine hemifumarate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na + /H + antiport. Rilmenidine hemifumarate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells [1] [2] [3] .

O=C(O)/C=C/C(O)=O.C1(NC(C2CC2)C3CC3)=NCCO1

-20°C

12352200