Rilpivirine-13C6

MedChem Express

Rilpivirine-13C6

5

Research Use Only

C16 13C6H18N6

372.37

Rilpivirine-13C6 (R278474-13C6) is 13C labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV[1][2].

CC1=CC(/C=C/C#N)=CC(C)=C1NC2=CC=NC(N[13C]3=[13CH][13CH]=[13C]([13CH]=[13CH]3)C#N)=N2

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