Rilpivirine-d6

MedChem Express

Rilpivirine-d6 [1312424-26-2]

10

1312424-26-2

Research Use Only

C22H12D6N6

372.46

Rilpivirine-d 6 is the deuterium labeled Rilpivirine. Rilpivirine (R278474) is a potent and specific diarylpyrimidine (DAPY) non-nucleoside reverse transcriptase inhibitor (NNRTI). Rilpivirine has high antiviral activity against wild-type HIV (EC50=0.4 nM) and mutant viruses (EC50=0.1-2.0 nM). Rilpivirine has a high genetic barrier to resistance development of HIV[1][2].

[2H]C([2H])([2H])C(C=C(C=C1C([2H])([2H])[2H])/C=C/C#N)=C1NC2=NC(NC3=CC=C(C=C3)C#N)=NC=C2

12352200