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Rineterkib

HY-114491
MedChem Express
CAS Number1715025-32-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight578.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Rineterkib [1715025-32-3]
  • Delivery Days Customer
    10
  • CAS Number
    1715025-32-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C26H27BrF3N5O2
  • Molecular Weight
    578.42
  • Scientific Description
    Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF [1] [2] .
  • SMILES
    O=C(N[C@@H](C1=CC(F)=CC(Br)=C1)CNC)C2=CC=C(C3=NC([C@@H]4C[C@H](F)[C@@H](O)CC4)=CN=C3N)C=C2F
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116134

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