RIPK1-IN-16 [2561431-77-2]

MedChem Express

RIPK1-IN-16 [2561431-77-2]

14

2561431-77-2

Research Use Only

C20H19N5O2S

393.46

RIPK1-IN-16 is an orally active and potent inhibitor of RIPK1. RIPK1-IN-16 inhibits excessive inflammation by blocking RIPK1-mediated necroptosis in vivo. RIPK1-IN-16 protects mouse from TNF-induced systemic inflammatory response syndrome and sepsis[1].

CN1C2=CC=CC=C2OC[C@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)C1=S

12352200