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ProductsBack/RIPK1-IN-4 [1481641-08-0]
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CgoaEGY7NO6EaEygAAAAAPjloqs483.png
CgoaEGY7NO6EaEygAAAAAPjloqs483.png

RIPK1-IN-4 [1481641-08-0]

Research Use Only
T12730
TargetMol Chemicals
CAS Number1481641-08-0
DownloadMSDS
Product group Chemicals
Molecular Weight401.46
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    RIPK1-IN-4 [1481641-08-0]
  • Delivery Days Customer
    9
  • CAS Number
    1481641-08-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    RIPK1-IN-4
  • Molecular Formula
    C23H23N5O2
  • Molecular Weight
    401.46
  • Scientific Description
    RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase).
  • Shelf life instruction
    3 years
  • SMILES
    CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cccc3c(N)nccc23)no1
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000

References

  • Harris PA, et al. Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis. ACS Med Chem Lett. 2013 Nov 4;4(12):1238-43.
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