RIPK3-IN-1 [2361139-70-8]

MedChem Express

RIPK3-IN-1 [2361139-70-8]

10

2361139-70-8

Research Use Only

99.30

C29H25FN4O4

512.53

RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. RIPK3-IN-1 inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 microM. RIPK3-IN-1 is also a c-Met kinase inhibitor with an IC50 of 1.1 microM[1].

O=C(C1=CC=CN(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=C4)C(C)=C3C

-20°C,2°C to 8°C

12352200