Riviciclib hydrochloride

MedChem Express

Riviciclib hydrochloride [920113-03-7]

10

920113-03-7

Research Use Only

99.08

C21H21Cl2NO5

438.307

Riviciclib hydrochloride (P276-00) is a potent cyclin-dependent kinase (CDK) inhibitor, which inhibits CDK9-cyclinT1 , CDK4-cyclin D1 , and CDK1-cyclinB with IC 50 s of 20 nM, 63 nM, and 79 nM, respectively [1] [2] . Riviciclib hydrochloride (P276-00) shows antitumor activity on cisplatin-resistant cells [3] .

[H]Cl.O=C1C=C(C2=CC=CC=C2Cl)OC3=C([C@@H]4CCN(C)[C@H]4CO)C(O)=CC(O)=C31

2°C to 8°C

12352200