RM 49 [113785-48-1]

MedChem Express

RM 49 [113785-48-1]

5

113785-48-1

Research Use Only

C16H20N4O6

364.35

RM 49 is the derivative of Mitomycin C (HY-13316). RM 49 exhibits cytotoxicity in SCLC and NSCLC lung cancer cells with IC50 of 0.01-0.5 microg/mL. RM 49 exhibits high relative antitumor activity in compared with Mitomycin C, Cisplatin (HY-17394), Carboplatin (HY-17393) and Doxorubicin (HY-15142)[1].

O=NC1=C(C2=C(C(OC)=C1C)N3[C@@](OC)([C@@H]2COC(N)=O)[C@H]4N[C@H]4C3)O

12352200