Bio-Connect

RMS5 [2497686-68-5]

HY-146097
MedChem Express
CAS Number2497686-68-5
Product group Chemicals
Molecular Weight598.75
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RMS5 [2497686-68-5]
  • Delivery Days Customer
    10
  • CAS Number
    2497686-68-5
  • Certification
    Research Use Only
  • Molecular Formula
    C35H38N2O5S
  • Molecular Weight
    598.75
  • Scientific Description
    RMS5, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS5 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS5 slightly diminishes the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS5 has strong anticancer property[1].
  • SMILES
    COC1=C(OC(C=C([C@@]2([H])CC3=CC=C(C=C3)O4)C(CCN2C)=C5)=C5OC)C([C@]6([H])CC7=CC4=CS7)=C(CCN6C)C=C1OC
  • UNSPSC
    12131703