RMS5 [2497686-68-5]
HY-146097
Overview
- SupplierMedChem Express
- Product NameRMS5 [2497686-68-5]
- Delivery Days Customer10
- CAS Number2497686-68-5
- CertificationResearch Use Only
- Molecular FormulaC35H38N2O5S
- Molecular Weight598.75
- Scientific DescriptionRMS5, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS5 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS5 slightly diminishes the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS5 has strong anticancer property[1].
- SMILESCOC1=C(OC(C=C([C@@]2([H])CC3=CC=C(C=C3)O4)C(CCN2C)=C5)=C5OC)C([C@]6([H])CC7=CC4=CS7)=C(CCN6C)C=C1OC
- UNSPSC12131703