RN-1747

MedChem Express

RN-1747 [1024448-59-6]

9

1024448-59-6

Research Use Only

99.25

C17H18ClN3O4S

395.86

RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 microM, 4.0 microM and 4.1 microM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 microM[1].

O=S(N1CCN(CC2=CC=CC=C2)CC1)(C3=CC=C(Cl)C=C3[N+]([O-])=O)=O

-20°C,2°C to 8°C

12352200