Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA019816ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA019816ESR1HU at dilution of 1:100
RNF11 Antibody
CSB-PA019816ESR1HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetRNF11
Overview
- SupplierCusabio
- Product NameRNF11 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID26994
- Target nameRNF11
- Target descriptionring finger protein 11
- Target synonymsCGI-123; RING finger protein 11; SID1669
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y3C5
- Protein NameRING finger protein 11
- Scientific DescriptionEssential component of a ubiquitin-editing protein complex, comprising also TNFAIP3, ITCH and TAX1BP1, that ensures the transient nature of inflammatory signaling pathways. Promotes the association of TNFAIP3 to RIPK1 after TNF stimulation. TNFAIP3 deubiquitinates Lys-63 polyubiquitin chains on RIPK1 and catalyzes the formation of Lys-48-polyubiquitin chains. This leads to RIPK1 proteasomal degradation and consequently termination of the TNF- or LPS-mediated activation of NF-kappa-B. Recruits STAMBP to the E3 ubiquitin-ligase SMURF2 for ubiquitination, leading to its degradation by the 26S proteasome.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
Related products
Product group Antibodies
ApplicationsWestern Blot
TargetRNF11
- SizePrice
Product group Antibodies
RNF11 Polyclonal AntibodyBS-9176R
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
TargetRNF11
- SizePrice