
WB analysis of mouse CD4 T cells using GTX46906 RNF128 antibody at 1:2400.
Lane:
1: CD4 T cell lysate from WT mice
2: CD4 T cell lysate from WT mice treated with anti-CD3/CD28
3: CD4 T cell lysate from WT mice treated with FK506
4: CD4 T cell lysate from WT mice treated with anti-CD3/CD28 and FK506
5: CD4 T cell lysate from TRPV1 KO mice
6: CD4 T cell lysate from TRPV1 KO mice treated with anti-CD3/CD28
7: CD4 T cell lysate from TRPV1 KO mice treated with FK506
8: CD4 T cell lysate from TRPV1 KO mice treated with anti-CD3/CD28 and FK506.
RNF128 antibody, C-term
GTX46906
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetRNF128
Overview
- SupplierGeneTex
- Product NameRNF128 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID79589
- Target nameRNF128
- Target descriptionring finger protein 128
- Target synonymsGRAIL, E3 ubiquitin-protein ligase RNF128, RING-type E3 ubiquitin transferase RNF128, gene related to anergy in lymphocytes protein, ring finger protein 128, E3 ubiquitin protein ligase
- HostRabbit
- IsotypeIgG
- Protein IDQ8TEB7
- Protein NameE3 ubiquitin-protein ligase RNF128
- Scientific DescriptionThe protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203





