
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA280050(RNF139 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)
RNF139 Antibody
CSB-PA280050
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetRNF139
Overview
- SupplierCusabio
- Product NameRNF139 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID11236
- Target nameRNF139
- Target descriptionring finger protein 139
- Target synonymsHRCA1, RCA1, TRC8, E3 ubiquitin-protein ligase RNF139, RING-type E3 ubiquitin transferase RNF139, multiple membrane spanning receptor TRC8, patched related protein translocated in renal cancer, translocation in renal carcinoma on chromosome 8 protein, translocation in renal carcinoma, chromosome 8
- HostRabbit
- IsotypeIgG
- Protein IDQ8WU17
- Protein NameE3 ubiquitin-protein ligase RNF139
- Scientific DescriptionThe protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161







