RNF14 antibody [N1C1]

GeneTex

RNF14 antibody [N1C1]

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

RNF14

ring finger protein 14

androgen receptor associated protein 54; ARA54; E3 ubiquitin-protein ligase RNF14; HFB30; HRIHFB2038; TRIAD2

Rabbit

IgG

E3 ubiquitin-protein ligase RNF14

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq]

Human

-20°C or -80°C,2°C to 8°C

12352203