RNF170 antibody, C-term

GeneTex

RNF170 antibody, C-term

9

WB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

RNF170

ring finger protein 170

ADSA; E3 ubiquitin-protein ligase RNF170; putative LAG1-interacting protein; RING-type E3 ubiquitin transferase RNF170; SNAX1

Rabbit

IgG

E3 ubiquitin-protein ligase RNF170

This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

-20°C or -80°C,2°C to 8°C

12352203