
WB analysis of Jurkat cells using GTX46901 RNF170 antibody at 0.2-1microg/ml.
RNF170 antibody, C-term
GTX46901
Overview
- SupplierGeneTex
- Product NameRNF170 antibody, C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID81790
- Target nameRNF170
- Target descriptionring finger protein 170
- Target synonymsADSA; E3 ubiquitin-protein ligase RNF170; putative LAG1-interacting protein; RING-type E3 ubiquitin transferase RNF170; SNAX1
- HostRabbit
- IsotypeIgG
- Protein IDQ96K19
- Protein NameE3 ubiquitin-protein ligase RNF170
- Scientific DescriptionThis gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203