RNF19A Antibody, Biotin conjugated

Cusabio

RNF19A Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

RNF19A

ring finger protein 19A, RBR E3 ubiquitin protein ligase

RNF19, E3 ubiquitin-protein ligase RNF19A, double ring-finger protein, protein p38 interacting with transcription factor Sp1, ring finger protein 19A, E3 ubiquitin protein ligase, ring-IBR-ring domain containing protein Dorfin

Rabbit

IgG

E3 ubiquitin-protein ligase RNF19A

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.

Human

-20°C or -80°C

41116161