IHC image of CSB-PA868327LA01HU diluted at 1:200 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA868327LA01HU diluted at 1:200 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
RNF19A Antibody
CSB-PA868327LA01HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetRNF19A
Overview
- SupplierCusabio
- Product NameRNF19A Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID25897
- Target nameRNF19A
- Target descriptionring finger protein 19A, RBR E3 ubiquitin protein ligase
- Target synonymsRNF19, E3 ubiquitin-protein ligase RNF19A, double ring-finger protein, protein p38 interacting with transcription factor Sp1, ring finger protein 19A, E3 ubiquitin protein ligase, ring-IBR-ring domain containing protein Dorfin
- HostRabbit
- IsotypeIgG
- Protein IDQ9NV58
- Protein NameE3 ubiquitin-protein ligase RNF19A
- Scientific DescriptionE3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR. Specifically ubiquitinates pathogenic SOD1 variants, which leads to their proteasomal degradation and to neuronal protection.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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