RNF7 antibody, Internal

GeneTex

RNF7 antibody, Internal

9

This antibody is expected to recognize isoform 1 (NP_055060.1).

WB: 1-3microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

RNF7

ring finger protein 7

CKBBP1; CKII beta-binding protein 1; rbx2; regulator of cullins 2; RING-box protein 2; ROC2; SAG; sensitive to apoptosis gene protein; sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2; zinc RING finger protein SAG

Goat

IgG

RING-box protein 2

The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203