Immunofluorescence analysis of MCF-7 cells using RNF7 Polyclonal Antibody
Immunofluorescence analysis of MCF-7 cells using RNF7 Polyclonal Antibody
RNF7 Polyclonal Antibody
E-AB-61633
Product group Antibodies
Overview
- SupplierElabscience
- Product NameRNF7 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- UNSPSC12352203