RNPS1 antibody
GTX129789
Overview
- SupplierGeneTex
- Product NameRNPS1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10921
- Target nameRNPS1
- Target descriptionRNA binding protein with serine rich domain 1
- Target synonymsE5.1; RNA binding protein with serine-rich domain; RNA-binding protein S1, serine-rich domain; RNA-binding protein with serine-rich domain 1; SR protein; SR-related protein LDC2
- HostRabbit
- IsotypeIgG
- Protein IDQ15287
- Protein NameRNA-binding protein with serine-rich domain 1
- Scientific DescriptionThis gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice.Read more
- XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence. Hou S et al., 2019 Sep 5, Nucleic Acids ResRead more
- Sumoylation is Required for the Cytoplasmic Accumulation of a Subset of mRNAs. Zhang H et al., 2014 Oct 20, Genes (Basel)Read more