Ro 09-1428 [134452-47-4]

MedChem Express

Ro 09-1428 [134452-47-4]

9

134452-47-4

Research Use Only

C31H31N11O10S3

813.84

Ro 09-1428 is a broad-spectrum parenteral cephalosporin. Ro 09-1428 has potent antibacterial activities against Pseudomonas aeruginosa and Acinetobacter caloaceticus, with MIC90s of 0.39 and 6.25 microg/mL, respectively, better than Ceftazidime (HY-B0593). Additionally, Ro 09-1428 shows high activity against Escherichia coli, Kkbsielia pneumoniae, Proteus mirabilis, P. aeruginosa, staphylococci, and more. Ro 09-1428 preferentially attacks PBP 3 for target in E. coli and P. aeruginosa, which is promising for research of septicemias and serious P. aeruginosa infections[1][2].

O=C(C1=C(CSC2N1C(C2NC(/C(C3=CSC(N)=N3)=N/OC(C)(C)C(NNC(C4=CC=C(C(O)=C4)O)=O)=O)=O)=O)CSC5=CC(C)=NC6=NC(CO)=NN65)O

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