Ro 14-9578 [100891-41-6]

MedChem Express

Ro 14-9578 [100891-41-6]

9

100891-41-6

Research Use Only

C16H13NO5

299.28

Ro 14-9578 is a tricyclic quinolone analog with antibacterial activity. Ro 14-9578 inhibits DNA biosynthesis (IC50=117 microM) and DNA supercoiling (IC50=66.8 microM) in Escherichia coli. Furthermore, Ro 14-9578 exhibits inhibitory effects against various Gram-negative bacteria and Staphylococcus aureus[1].

O=C(C1=CN2C(C3=C(CC2C)C=C4OCOC4=C3)=CC1=O)O

12352200