Ro 18-3981 [103295-92-7]

MedChem Express

Ro 18-3981 [103295-92-7]

9

103295-92-7

Research Use Only

C24H33N3O8S

523.60

Ro 18-3981 is a dihydropyridine that inhibits cardiac Ca2+ channels. Ro 18-3981 shows higher inhibitory activity when the cell membrane is in a depolarized state (Vh=-20 mV: IC50=2.3 nM; Vh=-50 mV: IC50=100 nM)[1].

O=C(C1=C(C)NC(C)=C(C(CS(=O)(NC(C)C)=O)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCCOCCC

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