Ro 23-3423 [110996-51-5]

MedChem Express

Ro 23-3423 [110996-51-5]

9

110996-51-5

Research Use Only

C23H22N4O2

386.45

Ro 23-3423 is a thromboxane synthase inhibitor with an IC50 value of 0.33 microM for human platelet microsomal thromboxane synthase. Ro 23-3423 increases plasma levels of PGF and PGE2 in a dose-dependent manner, accompanied by a decrease in mean systemic arterial pressure and systemic vascular resistance. Ro 23-3423 can be used in the study of general anesthesia[1].

O=C(NC(CCCC1=CC=CN=C1)C)C2=CN(C(C=C2)=N3)C=C4C3=CC=CC4=O

12352200