Ro 31-8220 [125314-64-9]
T6643L
Overview
- SupplierTargetMol Chemicals
- Product NameRo 31-8220 [125314-64-9]
- Delivery Days Customer72
- CAS Number125314-64-9
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameRo 31-8220
- Molecular FormulaC25H23N5O2S
- Molecular Weight457.55
- Scientific DescriptionRo 31-8220 is a potent inhibitor of PKC with IC50 values of 5, 24, 14, 27, 24, and 23 nM for PKCalpha, PKCbetaI, PKCbetaII, PKCgamma, PKCepsilon, and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3beta with IC50 values of 3, 8, 15, and 38 nM, respectively, without affecting MKK3, MKK4, MKK6, and MKK7.
- Shelf life instruction3 years
- SMILESO=C1C(C=2C=3C(N(CCCSC(=N)N)C2)=CC=CC3)=C(C(=O)N1)C=4C=5C(N(C)C4)=CC=CC5
- Storage Instruction-20°C
- UNSPSC12352200
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