RO-3306 [872573-93-8]

Name: RO-3306 [872573-93-8]
SKU: AG-CR1-3515_A27
Availability: BackOrder

AG-CR1-3515

CAS Number872573-93-8

Product group Chemicals

Estimated Purity>95%

Molecular Weight351.5

Overview

Supplier
AdipoGen Life Sciences
Product Name
RO-3306
Delivery Days Customer
10
CAS Number
872573-93-8
Certification
Research Use Only
Estimated Purity
>95%
Hazard Information
Warning
Molecular Formula
C18H13N3OS2
Molecular Weight
351.5
Scientific Description
Chemical. CAS: 872573-93-8. Formula: C18H13N3OS2. MW: 351.5. Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M . Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards. - Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A) [1-3, 5]. Potential anti-cancer compound [1, 8]. Cell cycle arrest inducer at G1, S and G2/M [2, 7] . Apoptosis inducer in embryonic stem cells [4]. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines [6]. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387 [8, 9]. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards [9].
SMILES
O=C1N=C(NCC2=CC=CS2)S\C1=C/C1=CC2=C(C=C1)N=CC=C2
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352200