RO4929097

MedChem Express

RO4929097 [847925-91-1]

5

847925-91-1

Research Use Only

99.01

C22H20F5N3O3

469.40

RO4929097 (RG-4733) is an orally active gamma secretase inhibitor with an IC50 of 4 nM, inhibiting cellular processing of Abeta40 and Notch with EC50 of 14 nM and 5 nM, respectively[1].

O=C(C(C)(C(NCC(F)(C(F)(F)F)F)=O)C)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3NC1=O

2°C to 8°C

12352200