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RO8191

HY-W063968
MedChem Express
CAS Number691868-88-9
DownloadMSDS
Product group Chemicals
Estimated Purity99.0
Molecular Weight373.21
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Overview

  • Supplier
    MedChem Express
  • Product Name
    RO8191 [691868-88-9]
  • Delivery Days Customer
    10
  • CAS Number
    691868-88-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C14H5F6N5O
  • Molecular Weight
    373.21
  • Scientific Description
    RO8191 (CDM-3008), an imidazonaphthyridine compound, is an orally active and potent interferon (IFN) receptor agonist. RO8191 directly binds to IFNalpha/beta receptor 2 (IFNAR2) and activates IFN-stimulated genes (ISGs) expression and JAK/STAT phosphorylation. RO8191 shows antiviral activity against both HCV and EMCV with an IC 50 of 200 nM for HCV replicon [1] . RO8191 is a cccDNA modulator (CDM) through interferon-like activity and has anti- HBV activity [2] .
  • SMILES
    FC(C1=C2C=CC3=NC(C4=NN=CO4)=CN3C2=NC(C(F)(F)F)=C1)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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