Rociletinib [1374640-70-6]

MedChem Express

Rociletinib [1374640-70-6]

10

1374640-70-6

Research Use Only

99.87

C27H28F3N7O3

555.55

Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1)=O

-20°C,2°C to 8°C

12352200