ROCK-IN-10

Biorbyt

ROCK-IN-10

10

1038549-25-5

Research Use Only

98.00%

C25H25N5O3

443.507

ROCK-IN-10 (compound 50) serves as a powerful inhibitor of ROCK, exhibiting IC50 values of 6 nM for ROCK1 and 4 nM for ROCK2, respectively. It demonstrates over 100-fold selectivity towards ROCK1 and ROCK2 when compared to other kinases [1].

NC(=O)c1ccc(NC(=O)NCc2cccc(c2)C(=O)Nc2ccc3CCNCc3c2)cc1

-20°C

12352200