ROCK inhibitor-2 [1127308-52-4]

MedChem Express

ROCK inhibitor-2 [1127308-52-4]

5

1127308-52-4

Research Use Only

99.92

C21H20N2O2

332.40

ROCK inhibitor-2 (compound 6) is a selective dual inhibitor of ROCK1 and ROCK2, with IC50 values of 160 nM and 21 nM, respectively. ROCK inhibitor-2 inhibits pMYPT1 with IC50 of 75 nM. ROCK inhibitor-2 exhibits antitumor activity[1][2].

O=C(N[C@H](C)C1=CC=CC(OC)=C1)C(C=C2)=CC=C2C3=CC=NC=C3

-20°C,2°C to 8°C

12352200