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ROCK1 Polyclonal Antibody

RD70331A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetRock1
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    ROCK1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    300 ug/ml
  • Conjugate
    Unconjugated
  • Gene ID19877
  • Target name
    Rock1
  • Target description
    Rho-associated coiled-coil containing protein kinase 1
  • Target synonyms
    1110055K06Rik; p160 ROCK-1; p160ROCK; Rho-associated coiled-coil forming kinase 1; rho-associated protein kinase 1; rho-associated, coiled-coil-containing protein kinase 1; rho-associated, coiled-coil-containing protein kinase I; Roc; Rock-I
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203