Rodatristat [1673568-73-4]

MedChem Express

Rodatristat [1673568-73-4]

10

1673568-73-4

Research Use Only

98.41

C27H27ClF3N5O3

561.98

Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice[1].

O=C([C@H]1NCC2(CCN(C3=NC(N)=NC(O[C@H](C4=CC=C(Cl)C=C4C5=CC=CC=C5)C(F)(F)F)=C3)CC2)C1)O

-20°C,2°C to 8°C

12352200