Rofecoxib [162011-90-7]
T1185
CAS Number162011-90-7
Product group Chemicals
Estimated Purity99.94%
Molecular Weight314.36
Overview
- SupplierTargetMol Chemicals
- Product NameRofecoxib [162011-90-7]
- Delivery Days Customer4
- CAS Number162011-90-7
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameRofecoxib
- Estimated Purity99.94%
- Molecular FormulaC17H14O4S
- Molecular Weight314.36
- Scientific DescriptionRofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2.
- Shelf life instruction3 years
- SMILESO=C1C(=C(CO1)C2=CC=C(S(C)(=O)=O)C=C2)C3=CC=CC=C3
- Storage Instruction-20°C
- UNSPSC12352200
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