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ProductsBack/Rolipram

Rolipram

M5939

CAS Number61413-54-5

Product group Chemicals

Estimated Purity>99%

Molecular Weight275.34

Overview

Supplier
AbMole BioScience
Product Name
Rolipram
Delivery Days Customer
9
CAS Number
61413-54-5
Certification
Research Use Only
Estimated Purity
>99%
Molecular Formula
C16H21NO3
Molecular Weight
275.34
Scientific Description
A selective inhibitor of PDE4, Rolipram, inhibits immunopurified PDE4B and PDE4D activity with IC50 of 130 nM and 240 nM, respectively. It has anti-inflammatory activity. Rolipram also increased cAMP levels and activated PKA, which in turn increased proteasome activity and inhibited tau aggregation.
SMILES
COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3
UNSPSC
12352200

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